Edward VI ( 12 of October 1537 to the 6th of July 1553 ) became King of England and Ireland on the 28th of January 1547 and was crowned on the 20th of February at the age on nine.
During Edward's reign the government was run by Regency Council, because he never because he never reached maturity.
The council was led by his uncle Edward Seymour, 1st Duke of somerset ( 1547 - 1549), and the by John Dudley, 1st Earl of Warwick ( 1550 - 1553), who later became Duke of Northumberland.
In April 1552 Edward contracted measles and smallpox, he never properly recovered.
On the 6th of July 1553, Edward died of tuberculosis, an infectious disease causes by a bacterium called mycobacterium tuberculosis, that infects the lungs and the organs in the central nervous system.